Ménière's Disease
Meniere’s disease (MD) is a syndrome affecting the inner ear.1 Initially, it usually afflicts only one ear, but both ears can be involved.1 Bilateral MD increases with duration of illness.1
MD should be considered a syndrome involving:1
- Severe vertigo often lasting several hours and associated with nausea and vomiting
- Fluctuating low-frequency hearing loss in the affected ear
- Tinnitus in the affected ear that may change pitch right before or during an attack
- A sense of ‘ear fullness’ in the affected ear
MD is not always due to a single mechanism or cause.1 Genetic, hormonal, viral and immune (both autoimmune and allergies) factors may play a role.1
MD usually develops between the ages of 30 and 50 years.1 It seldom affects children and onset in older people is rare.1 It appears to be more common in women.1
Acute episodes usually occur repeatedly, with a frequency of five to 10 per year, with remission stages that can last for months or years.1
Several comorbidities are associated with MD, such as autoimmune and autoinflammatory disorders (e.g. rheumatoid arthritis, systemic lupus, autoimmune hypothyroidism and psoriasis), migraine and anxiety.1
Although MD cannot be cured, its symptoms can be treated.1 Treatment includes effective management of the vertigo attacks and prevention of future MD episodes.1Symptom management should be personalized and should take into account age, disease duration, comorbidities, hearing stage and psychological impact on daily activities.1
Perez-Carpena P, Lopez-Escamez JA. Current Understanding and Clinical Management of Meniere’s Disease: A Systematic Review. Semin Neurol. 2020;40(01):138-150. doi:10.1055/s-0039-3402065