Allergic Rhinitis

Allergic rhinitis is a prevalent yet underappreciated inflammatory disorder of nasal mucosa, which is characterised by pruritus, sneezing, rhinorrhoea, and nasal congestion. It is mediated by early-phase and late-phase hypersensitivity responses—similar to those in allergic asthma—to indoor and outdoor environmental allergens.1

mother with baby

Although commonly regarded as merely a seasonal nuisance, allergic rhinitis can entail minimum persistent inflammation of mucosa, which synergizes with infective inflammation: thus, individuals with allergic rhinitis have additional difficulties with viral colds. In children, the combination of rhinoviral infection, allergic sensitization, and allergen exposure gives an odds ratio of 19 for admission to hospital for asthma.1

References

  1. G Alexander, H Peter, R Guiseppina, et al. Allergic Rhinitis. Lancet 2011; 378: 2112–22